The imunexin™ platform

A technology for creating next-generation multispecific biologics.

Platform overview

The imunexin™ platform

The imunexin™ platform enables the development of biologic medicines that can perform more than one therapeutic function within a single molecule.

This is achieved by attaching small engineered protein modules, known as imunexins™, to existing biologic drugs such as antibodies or enzymes.

By adding these modules, conventional single-target medicines can be converted into multispecific therapies capable of interacting with disease biology in more sophisticated ways.

Antibody Example: simple conversion of monospecific antibody drugs into bispecific antibody drugs

The existing monospecific antibodies can be:

  • Marketed antibody drugs off patent (acquired at no cost)
  • Failed pre-clinical and clinical stage antibody drugs (very reasonable terms)
  • New antibody drugs

Imunexins are small modular human proteins:

  • Can be designed to have therapeutic functions
  • Not affected by attaching them to other proteins
  • The protein they are attached remains unaffected

Protein Example: simple conversion of monospecific recombinant protein drugs into multispecific protein drugs

The existing protein drug can be:

  • Marketed recombinant protein drugs such as peptides and enzyme replacement therapies that are off patent (acquired at no cost)
  • Failed pre- and clinical stage recombinant protein drugs (very reasonable terms)
  • New enzyme-based therapies
Why multispecifics matter

Designed for diseases involving more than a single biological target

Many serious diseases involve multiple biological pathways rather than a single target.

Multispecific biologics are designed to address several disease mechanisms within a single therapy.

Multispecific drugs are one of the fastest-growing areas of biologic medicine and are attracting increasing interest from global pharmaceutical companies.

Imunexins have broad applicability

Applied across multiple biologic formats

The imunexin platform can be applied across multiple biologic formats, including:

  • antibodies
  • enzymes
  • cell-based therapies

This flexibility enables Imunexus to pursue programs across several disease areas including neurology, oncology, rare diseases and regenerative medicine.

The platform supports both internal drug development and strategic partnerships with pharmaceutical companies seeking to enhance existing biologic drugs.